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Project 1

Towards the Total Synthesis of the Anti-Malaria Drug Bielschowskysin

Supervisor: Prof. Johann Mulzer

Student: Jean-Baptiste Farcet

The aim of this project is to develop a synthetic route to Bielschowskysin, with a minimum of steps and high overall yield. The assignment of the absolute configuration as well as the possibility to provide diverse derivatives of the natural product is also of high priority. As the availability of the compound from the natural source is extremely limited due to environmental concerns, a synthetic approach appears of essence. The total synthesis will start from readily available and cheap material, should be stereo‐ and regioselective and apply new methodologies.

Initiativkolleg Functional Molecules
Währinger Str. 38
1090 Wien
T: +43 1 4277 70809
Universität Wien | Universitätsring 1 | 1010 Wien | T +43-1-4277-0